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Methylenetetrahydrofolate Reductase - an overview | ScienceDirect Topics

Beyond its metabolic role, FBP1 exhibits non-canonical functions in regulating mitosis, controlling cell cycle progression, and modulating c-Myc-dependent transcriptional programmes, thereby contributing to the persistence of drug-resistant cell populations on multiple fronts [100]

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doi: 10.1073/pnas.140213797

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